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This trial, Clinical Trials in Organ Transplantation 16 (CTOT‐16), sought to evaluate novel belatacept‐based strategies employing tacrolimus and corticosteroid avoidance. Sixty‐nine kidney transplant recipients were randomized from 4 US transplant centers comparing a control group of with rabbit antithymocyte globulin (rATG) induction, rapid steroid taper, and maintenance mycophenolate and tacrolimus, to 2 arms using maintenance belatacept. There were no graft losses but there were 2 deaths in the control group, us domestic supply fake. However, the trial was halted early because of rejection in the belatacept treatment groups. Serious adverse events were similar across groups.
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